C2.2 Neural signalling questions for IB Biology

42 questions on Neural signalling, written by Augment in the style of IB exam papers. Six of them are below in full, to answer on paper.

  • IB Biology
  • Part of C Interaction and interdependence
  • SL and HL

Questions by paper and level

SL and HL questions are for students at either level. HL only questions cover what only HL students study.

PaperSL and HLHL onlyAll
Paper 1A91120
Paper 1B325
Paper 251217
Every paper172542

Counted on

Questions to try

Written by Augment in the style of IB exams, not past papers. Answer them on paper, then check each one against its markscheme with a free account.

Question 1 · BIO-00793Paper 1A · 1 mark

Which statement describes the structure of a typical motor neuron?

  1. A

    Several long axons carry impulses towards a cell body that has no nucleus

  2. B

    A cell body containing the nucleus has many short dendrites and one long axon

  3. C

    A single long dendrite carries impulses away from the cell body to an effector

  4. D

    Many long axons and one short dendrite project from the cell body

Question 2 · BIO-00813Paper 1B · 8 marks

Researchers investigated the relationship between axon diameter and the speed of nerve impulses in non-myelinated axons. Single axons were dissected from eight species of marine invertebrate, including the giant axon of a squid. Each axon was kept in seawater at 18 °C, stimulated at one end, and the time taken for the impulse to reach a recording electrode a known distance away was used to calculate the conduction speed. The graph shows the mean conduction speed for each axon.

Scatter graph with best-fit line: conduction speed rises from 5.2 m/s at 20 μm diameter to 25.6 m/s at 500 μm, a strong positive correlation.

The correlation coefficient (r) for these data is 0.98.

  1. (a)

    State one variable that was controlled in this investigation.

    1 mark

  2. (b)

    Calculate the coefficient of determination (R2) and outline what it shows about these data.

    2 marks

  3. (c)

    Describe the relationship between axon diameter and conduction speed shown in the graph.

    2 marks

  4. (d)

    A student concluded that a wider axon causes a faster nerve impulse. Outline why a correlation alone does not show this.

    1 mark

  5. (e)

    Myelinated axons in mammals with a diameter of 10 μm conduct impulses at about 50 m s-1. Using the data, outline how the conduction speed of these axons differs from that of the non-myelinated axons, and suggest one advantage of myelination for a vertebrate.

    2 marks

Question 3 · BIO-00135Paper 2 · HL only · 9 marks

The table shows estimates of the number of motor neurons supplying three human skeletal muscles and the number of muscle fibres in each muscle.

Muscle

Number of motor neurons

Number of muscle fibres

Mean number of fibres per motor unit

muscle that moves the eyeball

2 970

27 000

9

muscle that moves the index finger

120

40 800

340

calf muscle that raises the heel

580

1 040 000

  1. (a)

    Calculate the mean number of fibres per motor unit in the calf muscle.

    1 mark

  2. (b)

    State the name of the junction between a motor neuron and a muscle fibre.

    1 mark

  3. (c)

    Suggest, using the data, why the muscle that moves the eyeball has small motor units.

    2 marks

  4. (d)

    Explain how the force of contraction of the calf muscle can be varied.

    2 marks

  5. (e)

    Describe the events at a neuromuscular junction that lead to depolarization of the muscle fibre membrane.

    3 marks

Question 4 · BIO-00794Paper 1A · 1 mark

How does the sodium–potassium pump help to establish the resting potential of a neuron?

  1. A

    It uses energy from ATP to pump sodium ions into the neuron and potassium ions out

  2. B

    It allows sodium and potassium ions to diffuse down their concentration gradients

  3. C

    It uses energy from ATP to pump both sodium and potassium ions out of the neuron

  4. D

    It uses energy from ATP to pump sodium ions out of the neuron and potassium ions in

Question 5 · BIO-00814Paper 1B · 8 marks

Ouabain is a chemical that binds to sodium–potassium pumps and stops them working. Students used data from an experiment on isolated crab (Carcinus maenas) nerve fibres. Five fibres were kept in an oxygenated saline solution with ouabain added at time 0, and five control fibres were kept in the same solution without ouabain. The resting potential of each fibre was recorded every 20 minutes using a microelectrode. The graph shows the mean resting potential ± standard deviation.

Line graph of mean resting potential against time. Control stays at about −70 mV for 120 min. With ouabain it falls from −70 mV to −68 mV at 20 min, then steadily to −35 mV at 120 min.
  1. (a)

    State the dependent variable in this experiment.

    1 mark

  2. (b)

    The mean resting potential of the fibres treated with ouabain changed from −70 mV to −35 mV over 120 minutes. Calculate the percentage decrease in the size of the resting potential.

    1 mark

  3. (c)

    Using the error bars, discuss whether ouabain had a significant effect on the resting potential after 20 minutes and after 120 minutes.

    2 marks

  4. (d)

    Explain why the resting potential of the fibres treated with ouabain became less negative gradually rather than immediately.

    3 marks

  5. (e)

    Suggest why the saline solution was oxygenated for both groups of fibres.

    1 mark

Question 6 · BIO-00142Paper 2 · HL only · 15 marks

Movement in animals depends on the coordinated action of nerves, muscles and bones.

  1. (a)

    Outline how an action potential is propagated along an axon.

    4 marks

  2. (b)

    Explain how skeletal muscle fibres contract, using the sliding filament model.

    7 marks

  3. (c)

    Describe the structure of the human hip joint.

    4 marks

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The notes on C2.2 Neural signalling

More questions in Interaction and interdependence

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  2. C1.2Cell respiration
  3. C1.3Photosynthesis
  4. C2.1Chemical signallingHL only
  5. C2.2Neural signallingThis page
  6. C3.1Integration of body systems
  7. C3.2Defence against disease
  8. C4.1Populations and communities
  9. C4.2Transfers of energy and matter

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